New! Research abstracts on CBG

  • Neural Inflammation CBG Abstracts
  • Appetite Stimulation CBG Abstracts
  • GI Tract CBG Abstracts

Canine Cannabinoid Research

  • A report of adverse effects associated with the administration of cannabidiol in healthy dogs.
  • Consumers’ perceptions of hemp products for animals.
  • Pharmacokinetics, safety and clinical efficacy of Cannabidiol treatment in osteoarthritic dogs
  • A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain

  • Pharmacokinetics of cannabidiol administered by 3 delivery methods at 2 dosages to healthy dogs.
  • The Endocannabinoid System of Animals
  • JAHVMA: Cannabis-in-Veterinary-Medicine-A-Critical-Review-Vol-61_LR-3-2

Cannabinoid Receptors and Dosing

  • Cannabinoids and Cytochrome P450 Interactions

  • Overcoming the bell-shaped dose-response of cannabidiol by using cannabis extract enriched in cannabidiol.
  • Localization of cannabinoid receptors CB1, CB2, GPR55, and PPARα in the canine gastrointestinal tract.
  • Upregulation of CB2 receptors in reactive astrocytes in canine degenerative myelopathy, a disease model of ALS
  • Absence of Entourage:Terpenoids Commonly Found in Cannabis sativa Do Not Modulate the Functional Activity of D9-THC at Human CB1 and CB2 Receptors

     

Cannabinoid Clinical Applications

  • Opportunities for cannabis in supportive care in cancer
  • Immune responses regulated by cannabidiol
  • Emerging Role of the CB2 Cannabinoid Receptor in Immune Regulation and Therapeutic Prospects
  • Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunumodulation
  • The gastrointestinal tract – a central organ of cannabinoid signaling in health and disease

Curcumin Bioavailability

  • Bioavailable curcumin formulations: A review of pharmacokinetic studies in healthy volunteers.
  • Recent developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin: the Golden Pigment from Golden Spice.
  • The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes

Curcumin & Arthritis Clinical Studies

  • Micellar solubilisation enhances the anti-inflammatory activities of Curcumin and boswellic acids in fats with adjuvant-induced arthritis.
  • A novel highly bioavailable curcumin formulation improves symptoms and diagnostic indicators in rheumatoid arthritis patient: a randomized, double-blind, placebo-controlled, two-dose, three-arm and parallel-group study.

Curcumin Clinical Applications

  • Mechanisms of apoptosis modulation by curcumin: implications for cancer therapy.
  • Curcumin Micelles Improve Mitochondrial Function in a Mouse Model of Alzheimer’s Disease.
  • Transepithelial Transport of Curcumin in Caco-2 Cells Is significantly Enhanced by Micellar Solubilisation