Botanical Pain Solutions for Pets and Horses


Endocannabinoid Support Formulas 900 & 1800

The endo-cannabinoid system (ECS) is found in most animals, helping the nervous system and the immune system communicate to keep the body functioning normally.  The ECS is involved with mood regulation, relieving pain, fighting cancer, metabolic balance and GI motility.   Plant cannabinoids from hemp can interact with the ECS, providing pain relief, soothing the nervous system and reducing inflammation.   Cannabidiol (CBD) is not psycho-active but has similar health benefits to THC.  Industrial hemp, a cannabis plant with less than 0.3% THC, is legal to grow, use and sell in the USA.  The principle cannabinoid found in industrial hemp, CBD, will not get a person or a dog “high”, but will help with anxiety, pain, mobility, inflammation and seizure regulation.

How to dose CBD?

CBD oil is easily absorbed through the mucus membranes of the mouth, tongue and gums.  However, CBD on food or in treats is far less bioavailable, because it passes through liver detox and 80-90% is broken down.  So, for best results, give CBD oil directly into the mouth.  Twice a day dosing works best for most animals, and research shows that CBD is very safe in pets, even at high doses.

Why use CBD?

Many health problems in humans and animals involve nervous system and immune system regulation.  Some neuro-degenerative diseases may even be caused by ECS poor function.  CBD is most commonly used for reducing anxiety and phobias, helping arthritis pain and inflammation, helping regulating seizures and diabetes, and soothing nerve pain.*

Dose by body weight Indications
Micro (0.1 mg/kg) Anxiety, fear, stress, behavioral issues, mild pain, muscle tension
Medium (0.2-0.5 mg/kg) Arthritis, moderate pain, muscle spasms
High (0.5-1.0 mg/kg) Moderate to severe pain, nerve pain, DM, tremors, epilepsy, diabetes regulation, IBD
Ultra (1.0-5.0 mg/kg) Uncontrolled epilepsy, cancer, extreme pain, hospice


These doses represent a good starting point, but there can be individual variation.  Monitor response after 3 days— dosage may need to be modified up or down to achieve best results.

In horses, pain and anxiety can be treated with as little as 20-25 mg CBD oil administered, rubbed onto the gums, once or twice a day.

How to calculate your pet’s CBD dose

Wlb ➗ 2.2 = Wkg        Dosage x Wkg = Dose

For example: Your 65 lb Lab is 12 years old, and can no longer jump into the car, hesitates on stairs.  But still wants to play.

Dosage level: Medium, start with 0.25 mg/kg

66 lb divided by 2.2 lb/kg = 30 kg,  30 kg x 0.25 mg/kg = 7.5 mg

Using ECS900 (30 mg/ml), each drop has 1 mg, so the dose given twice a day should be 8 drops or 1/4 ml.

Using ECS600 (20 mg/ml), each drop has 0.67 mg, so the dose given twice daily should be 11 drops or 1/3 ml.

Plena Curae products are always 3rd party lab tested, 100% THC-free, and made in a GMP facility.